Publications

The TruEffect team has a proven track record of publishing high-quality research in Canadian and international scientific journals. Below is a sample of our work.

Coming soon

Farhat, N., Tsaioun, K., Saunders-Hastings, P., Morgan, R. L., Ramoju, S., Hartung, T., & Krewski, D. (2021). Systematic review in evidence-based risk assessment. Altex. https://doi.org/10.14573/altex.2004111 

Kelly, D. J., Thibault, D., Tam, D., Liu, L. J. W., Cragg, J. J., Willis, A. W., & Crispo, J. A. G. (2021). Readmission Following Hospitalization for Traumatic Brain Injury: A Nationwide Study. J Head Trauma Rehabil. https://doi.org/10.1097/htr.0000000000000699

Crispo, J. A. G., Lam, M., Le, B., Shariff, S. Z., Ansell, D. R., Squarzolo, M., Ouellette, D., Thibault, D. P., Marras, C., Willis, A. W., & Seitz, D. (2021). Survival and Health Care Use After Deep Brain Stimulation for Parkinson’s Disease. Can J Neurol Sci, 48(3), 372-382. https://doi.org/10.1017/cjn.2020.187 

Farhat, A., Farhat, N., Abou Yassine, W., Halat, R., & El Khatib, S. (2021). University Instructors’ Perceptions toward Online Teaching at the Onset of the COVID-19 Outbreak in Lebanon: A Descriptive Study. Middle Eastern Journal of Research in Education and Social Sciences, 2(2), 37-57, 2(2), 37-57. https://doi.org/10.47631/mejress.v2i2.243 

Taher, M. K., Crispo, J. A. G., Fortin, Y., Moog, R., McNair, D., Bjerre, L. M., . . . Krewski, D. (2021). Systemic quinolones and risk of acute liver failure III: A nested case-control study using a US electronic health records database. J Gastroenterol Hepatol, 36(8), 2307-2314. https://doi.org/10.1111/jgh.15504

Crispo, J. A. G., Lam, M., Le, B., Richard, L., Shariff, S. Z., Ansell, D. R., Squarzolo, M., Marras, C., Willis, A. W., & Seitz, D. (2020). Disparities in Deep Brain Stimulation Use for Parkinson’s Disease in Ontario, Canada. Can J Neurol Sci, 47(5), 642-655. https://doi.org/10.1017/cjn.2020.79 

Ellis, D. E., Zaoutis, T., Thibault, D. P., Crispo, J. A. G., Abraham, D. S., & Willis, A. W. (2020). Readmissions after hospital care for meningitis in the United States. Am J Infect Control, 48(7), 798-804. https://doi.org/10.1016/j.ajic.2019.10.025 

Farhat, N., Al Ruwaili, H., Gogna, P., Habash, M., Taher, M., Sikora, L., Habash, R., Momoli, F., Villeneuve, P., & Krewski, D. (2020). Systematic review of exposure to radiofrequency fields and cancer. . PROSPERO, CRD42020202914 

Farhat, N., Birkett, N., Haddad, N., Fortin, Y., Momoli, F., Wen, S. W., Wielgosz, A., McNair, D. S., Mattison, D. R., & Krewski, D. (2020). Risk of Adverse Cardiovascular Events Following a Myocardial Infarction in Patients Receiving Combined Clopidogrel and Proton Pump Inhibitor Treatment: A Nested Case-Control Study. Drugs Real World Outcomes, 7(3), 191-203. https://doi.org/10.1007/s40801-020-00204-9 

Fullard, M., Thibault, D., Zisling, H., Crispo, J. A., & Willis, A. (2020). Parkinson Disease Associated Differences in Elective Orthopedic Surgery Outcomes: A National Readmissions Database Analysis. J Parkinsons Dis, 10(4), 1577-1586. https://doi.org/10.3233/jpd-201992 

Kessler, S. K., Blank, L. J., Glusman, J., Thibault, D., Massey, S., Abend, N. S., Szperka, C. L., Crispo, J. A. G., & Willis, A. W. (2020). Unplanned Readmissions of Children With Epilepsy in the United States. Pediatr Neurol, 108, 93-98. https://doi.org/10.1016/j.pediatrneurol.2020.01.010 

Liu, L. J. W., Bach, P., Crispo, J. A. G., Kramer, J. L. K., & Cragg, J. J. (2020). A Population Study of Prescribed Opioid-based Pain Reliever Use among Individuals with Mood and Anxiety Disorders in Canada. Drug Alcohol Depend, 216, 108229. https://doi.org/10.1016/j.drugalcdep.2020.108229 

Mendizabal, A., Thibault, D. P., Crispo, J. A., Paley, A., & Willis, A. W. (2020). Comorbid disease drives short-term hospitalization outcomes in patients with multiple sclerosis. Neurol Clin Pract, 10(3), 255-264. https://doi.org/10.1212/cpj.0000000000000838 

Ohle, R., Yan, J. W., Yadav, K., Cournoyer, A., Savage, D. W., Jetty, P., Atoui, R., Bittira, B., Wilson, B., Gupta, A., Coffey, N., Callaway, Y., Middaugh, J., Ansell, D., Rubens, F., Bignucolo, S. J., Scott, T. M., McIsaac, S., & Lang, E. (2020). Diagnosing acute aortic syndrome: a Canadian clinical practice guideline. Cmaj, 192(29), E832-e843. https://doi.org/10.1503/cmaj.200021 

Schneider, R. B., Jimenez-Shahed, J., Abraham, D. S., Thibault, D. P., Mantri, S., Fullard, M., Burack, M. A., Chou, K. L., Spindler, M., Jermakowicz, W. J., D’Haese, P. F., York, M. K., Kirk, J. C., Schwalb, J. M., Espay, A. J., Shih, L. C., Simon, D. K., Hunter, C., Crispo, J. A. G., & Willis, A. W. (2020). Acute readmission following deep brain stimulation surgery for Parkinson’s disease: A nationwide analysis. Parkinsonism Relat Disord, 70, 96-102. https://doi.org/10.1016/j.parkreldis.2019.11.023 

Taher, M. K., Farhat, N., Karyakina, N. A., Shilnikova, N., Ramoju, S., Gravel, C. A., Krishnan, K., Mattison, D., Wen, S. W., & Krewski, D. (2020). Data on systematic review and meta-analysis of epidemiologic evidence on the association between perineal use of talc powder and risk of ovarian cancer. Data Brief, 29, 105277. https://doi.org/10.1016/j.dib.2020.105277 

Zheng, R., Rios-Diaz, A. J., Thibault, D. P., Crispo, J. A. G., Willis, A. W., & Willis, A. I. (2020). A contemporary analysis of goiters undergoing surgery in the United States. Am J Surg, 220(2), 341-348. https://doi.org/10.1016/j.amjsurg.2020.01.005

Bignucolo, A., Parent, A., Dube, M., Kusnierczyk, J., Ansell, D., & Ohle, R. (2019). Triple-sequential defibrillation for refractory ventricular fibrillation in a 24-year-old male out of hospital cardiac arrest. CJEM, 21(6), 809-811. https://doi.org/10.1017/cem.2019.415 

Crispo, J. A. G., Thibault, D. P., & Willis, A. W. (2019). Adverse Drug Events as a Reason for Adult Hospitalization: A Nationwide Readmission Study. Ann Pharmacother, 53(6), 557-566. https://doi.org/10.1177/1060028018818571 

Farhat, N., Fortin, Y., Haddad, N., Birkett, N., Mattison, D. R., Momoli, F., Wu Wen, S., & Krewski, D. (2019). Systematic review and meta-analysis of adverse cardiovascular events associated with proton pump inhibitors used alone or in combination with antiplatelet agents. Crit Rev Toxicol, 49(3), 215-261. https://doi.org/10.1080/10408444.2019.1583167 

Farhat, N., Haddad, N., Crispo, J., Birkett, N., McNair, D., Momoli, F., Wen, S. W., Mattison, D. R., & Krewski, D. (2019). Trends in concomitant clopidogrel and proton pump inhibitor treatment among ACS inpatients, 2000-2016. Eur J Clin Pharmacol, 75(2), 227-235. https://doi.org/10.1007/s00228-018-2564-8 

Kadry Taher, M., Farhat, N., Karyakina, N. A., Shilnikova, N., Ramoju, S., Gravel, C. A., Krishnan, K., Mattison, D., Wen, S. W., & Krewski, D. (2019). Critical review of the association between perineal use of talc powder and risk of ovarian cancer. Reprod Toxicol, 90, 88-101. https://doi.org/10.1016/j.reprotox.2019.08.015 

Rios-Diaz, A. J., Zheng, R., Thibault, D. P., Crispo, J. A. G., Willis, A. W., & Willis, A. I. (2019). Understanding nationwide readmissions after thyroid surgery. Surgery, 165(2), 423-430. https://doi.org/10.1016/j.surg.2018.09.007

Blank, L. J., Crispo, J. A. G., Thibault, D. P., Davis, K. A., Litt, B., & Willis, A. W. (2018). Readmission after seizure discharge in a nationally representative sample. Neurology, 92(5), e429-442. https://doi.org/10.1212/wnl.0000000000006746 

Crispo, J. A. G., Thibault, D. P., Fortin, Y., Krewski, D., & Willis, A. W. (2018). Association between medication-related adverse events and non-elective readmission in acute ischemic stroke. BMC Neurol, 18(1), 192. https://doi.org/10.1186/s12883-018-1195-0 

Crispo, J. A. G., Thibault, D. P., Fortin, Y., & Willis, A. W. (2018). Inpatient care for stiff person syndrome in the United States: a nationwide readmission study. J Clin Mov Disord, 5, 5. https://doi.org/10.1186/s40734-018-0071-9 

Ramchand, P., Thibault, D. P., Crispo, J. A., Levine, J., Hurst, R., Mullen, M. T., Kasner, S., & Willis, A. W. (2018). Readmissions After Mechanical Thrombectomy for Acute Ischemic Stroke in the United States: A Nationwide Analysis. J Stroke Cerebrovasc Dis, 27(10), 2632-2640. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.05.035

Ansell, D., Crispo, J. A. G., Simard, B., & Bjerre, L. M. (2017). Interventions to reduce wait times for primary care appointments: a systematic review. BMC Health Serv Res, 17(1), 295. https://doi.org/10.1186/s12913-017-2219-y 

Fortin, Y., Crispo, J., Cohen, D., Dahrouge, S., McNair, D., Mattison, D., & Krewski, D. (2017). An exposure–response relationship between multimorbidity and motor-vehicle accidents. Journal of Transport & Health, 4. https://doi.org/10.1016/j.jth.2017.01.006 

Fortin, Y., Crispo, J., Cohen, D., McNair, D., Mattison, D., & Krewski, D. (2017). Optimal look back period and summary method for Elixhauser comorbidity measures in a US population-based electronic health record database. Open Access Medical Statistics, Volume 7, 1-13. https://doi.org/10.2147/OAMS.S120426 

Fortin, Y., Crispo, J. A., Cohen, D., McNair, D. S., Mattison, D. R., & Krewski, D. (2017). External validation and comparison of two variants of the Elixhauser comorbidity measures for all-cause mortality. PLoS One, 12(3), e0174379. https://doi.org/10.1371/journal.pone.0174379 

Krewski, D., Barakat-Haddad, C., Donnan, J., Martino, R., Pringsheim, T., Tremlett, H., van Lieshout, P., Walsh, S. J., Birkett, N. J., Gomes, J., Little, J., Bowen, S., Candundo, H., Chao, T. K., Collins, K., Crispo, J. A. G., Duggan, T., El Sherif, R., Farhat, N., Fortin, Y., Gaskin, J., Gupta, P., Hersi, M., Hu, J., Irvine, B., Jahanfar, S., MacDonald, D., McKay, K., Morrissey, A., Quach, P., Rashid, R., Shin, S., Sikora, L., Tkachuk, S., Taher, M. K., Wang, M. D., Darshan, S., & Cashman, N. R. (2017). Determinants of neurological disease: Synthesis of systematic reviews. Neurotoxicology, 61, 266-289. https://doi.org/10.1016/j.neuro.2017.04.002 

Martino, R., Candundo, H., Lieshout, P. V., Shin, S., Crispo, J. A. G., & Barakat-Haddad, C. (2017). Onset and progression factors in Parkinson’s disease: A systematic review. Neurotoxicology, 61, 132-141. https://doi.org/10.1016/j.neuro.2016.04.003 

Saunders-Hastings, P., Crispo, J. A. G., Sikora, L., & Krewski, D. (2017). Effectiveness of personal protective measures in reducing pandemic influenza transmission: A systematic review and meta-analysis. Epidemics, 20, 1-20. https://doi.org/10.1016/j.epidem.2017.04.003

Crispo, J. A., Willis, A. W., Thibault, D. P., Fortin, Y., Hays, H. D., McNair, D. S., Bjerre, L. M., Kohen, D. E., Perez-Lloret, S., Mattison, D. R., & Krewski, D. (2016). Associations between Anticholinergic Burden and Adverse Health Outcomes in Parkinson Disease. PLoS One, 11(3), e0150621. https://doi.org/10.1371/journal.pone.0150621 

Crispo, J. A. G., Willis, A. W., Thibault, D. P., Fortin, Y., Emons, M., Bjerre, L. M., Kohen, D. E., Perez-Lloret, S., Mattison, D., & Krewski, D. (2016). Associations Between Cardiovascular Events and Nonergot Dopamine Agonists in Parkinson’s Disease. Mov Disord Clin Pract, 3(3), 257-267. https://doi.org/10.1002/mdc3.12286 

Thibault, D. P., Mendizabal, A., Abend, N. S., Davis, K. A., Crispo, J., & Willis, A. W. (2016). Hospital care for mental health and substance abuse in children with epilepsy. Epilepsy Behav, 57(Pt A), 161-166. https://doi.org/10.1016/j.yebeh.2016.01.031

Crispo, J. A., Fortin, Y., Sikora, L., Kohen, D. E., Bjerre, L. M., Mattison, D. R., Perez-Lloret, S., Hessian, R. C., Willis, A. W., & Krewski, D. (2015). Non-ergot dopamine agonists and the risk of heart failure and other adverse cardiovascular reactions in Parkinson’s disease (Protocol). Cochrane Database of Systematic Reviews(9), Art. No.: CD011843. https://doi.org/10.1002/14651858.CD011843 

Crispo, J. A., Fortin, Y., Thibault, D. P., Emons, M., Bjerre, L. M., Kohen, D. E., Perez-Lloret, S., Mattison, D., Willis, A. W., & Krewski, D. (2015). Trends in inpatient antiparkinson drug use in the USA, 2001-2012. Eur J Clin Pharmacol, 71(8), 1011-1019. https://doi.org/10.1007/s00228-015-1881-4 

Nguyen, P., Khurana, S., Peltsch, H., Grandbois, J., Eibl, J., Crispo, J., Ansell, D., & Tai, T. C. (2015). Prenatal glucocorticoid exposure programs adrenal PNMT expression and adult hypertension. J Endocrinol, 227(2), 117-127. https://doi.org/10.1530/joe-15-0244

Ansell, D., Grandbois, J., & Tai, T. (2014). Gene Regulation of Catecholamine Biosynthetic Enzymes by Nitric Oxide in PC12 Cells. Open Journal of Endocrine and Metabolic Diseases, 04, 77-84. https://doi.org/10.4236/ojemd.2014.44009 

Perez-Lloret, S., Rey, M. V., Crispo, J., Krewski, D., Lapeyre-Mestre, M., Montastruc, J. L., & Rascol, O. (2014). Risk of heart failure following treatment with dopamine agonists in Parkinson’s disease patients. Expert Opin Drug Saf, 13(3), 351-360. https://doi.org/10.1517/14740338.2014.888057 

Thiruganasambandamoorthy, V., Turko, E., Ansell, D., Vaidyanathan, A., Wells, G. A., & Stiell, I. G. (2014). Risk factors for serious underlying pathology in adult emergency department nontraumatic low back pain patients. J Emerg Med, 47(1), 1-11. https://doi.org/10.1016/j.jemermed.2013.08.140

Ansell, D. R., & Giles, S. M. (2013). The occasional femoral line. Can J Rural Med, 18(3), 101-106. https://www.researchgate.net/publication/242652290_The_occasional_femoral_line  

Farhat, N., Ramsay, T., Jerrett, M., & Krewski, D. (2013). Short-Term Effects of Ozone and PM2.5 on Mortality in 12 Canadian Cities. Journal of Environmental Protection, 04, 18-32.   https://doi.org/10.4236/jep.2013.412A1003 

Jull, J., Crispo, J., Welch, V., Macdonald, H., Brascoupé, S., Boyer, Y., & Stacey, D. (2013). Interventions for Indigenous Peoples Making Health Decisions: A Systematic Review. Pimatisiwin, 11. https://www.researchgate.net/publication/263442948_Interventions_for_Indigenous_Peoples_Making_Health_Decisions_A_Systematic_Review 

Crispo, J. A., Ansell, D. R., Ubriaco, G., & Tai, T. C. (2011). Role of reactive oxygen species in the neural and hormonal regulation of the PNMT gene in PC12 cells. Oxid Med Cell Longev, 2011, 756938. https://doi.org/10.1155/2011/756938

Crispo, J. A., Ansell, D. R., Piche, M., Eibl, J. K., Khaper, N., Ross, G. M., & Tai, T. C. (2010). Protective effects of polyphenolic compounds on oxidative stress-induced cytotoxicity in PC12 cells. Can J Physiol Pharmacol, 88(4), 429-438. https://doi.org/10.1139/y09-137 

Crispo, J. A., Piché, M., Ansell, D. R., Eibl, J. K., Tai, I. T., Kumar, A., Ross, G. M., & Tai, T. C. (2010). Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells. Biochem Biophys Res Commun, 393(4), 773-778. https://doi.org/10.1016/j.bbrc.2010.02.079 

Farhat, N., Krewski, D., & Tyshenko, M. (2010). Bovine spongiform encephalopathy and its management in Israel. International Journal of Risk Assessment and Management, 14(3/4), 203-211. https://doi.org/10.1504/IJRAM.2010.035266 

Farhat, N., Krewski, D., & Tyshenko, M. (2010). Risk assessment and risk management of bovine spongiform encephalopathy in Portugal. International Journal of Risk Assessment and Management, 14(1/2), 133-144. https://doi.org/10.1504/IJRAM.2010.035250 

Tyshenko, M., Farhat, N., Lewis, R., Shilnikova, N., & Krewski, D. (2010). Applying a precautionary risk management strategy for regulation of nanotechnology. International Journal of Nanotechnology, 7(2/3), 243-264. https://doi.org/10.1504/IJNT.2010.031313

Nguyen, P., Peltsch, H., de Wit, J., Crispo, J., Ubriaco, G., Eibl, J., & Tai, T. C. (2009). Regulation of the phenylethanolamine N-methyltransferase gene in the adrenal gland of the spontaneous hypertensive rat. Neurosci Lett, 461(3), 280-284. https://doi.org/10.1016/j.neulet.2009.06.022

Gauthier, M. A., Eibl, J. K., Crispo, J. A., & Ross, G. M. (2008). Covalent arylation of metallothionein by oxidized dopamine products: a possible mechanism for zinc-mediated enhancement of dopaminergic neuron survival. Neurotox Res, 14(4), 317-328. https://doi.org/10.1007/bf03033856

Perez-Lloret S., Crispo J.A.G., Rey M.V., Mattison D., Krewski D. (2021) Value and Methods of Pharmacovigilance in the Monitoring of Drug Safety in Parkinson’s Disease. In: Perez-Lloret S. (eds) Clinical Trials In Parkinson’s Disease. Neuromethods, vol 160. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0912-5_8

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